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Caspase12 rabbit pAb

簡要描述：SourceRabbitApplicationsWB,IHC,ELISAReactivityHumanDilutionWB:1:500-1:2000

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2025-07-27
  • 訪  問  量：161

詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB,IHC,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Caspase12 Polyclonal Antibody detects endogenous levels of Caspase12 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human Caspase12. AA range:50-99

  • Uniprot No

    Q6UXS9

  • Alternative names

    CASP12; Inactive caspase-12; CASP-12

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    caspase 12 (gene/pseudogene)(CASP12) Homo sapiens Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011],

  • Other

    CASP12, Inactive caspase-12

  • Mol.Wt (Da)

    38907/29429

  • Concentration

    1 mg/ml

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