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Atm (phospho Ser1981) rabbit pAb

簡(jiǎn)要描述：SourceRabbitApplicationsWB,IHC,ELISAReactivityHuman,MouseDilutionWB:1:500-1:2000

  • 產(chǎn)品型號(hào)：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2025-07-01
  • 訪  問(wèn)  量：29

詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB,IHC,ELISA

  • Reactivity

    Human,Mouse

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-Atm (S1981) Polyclonal Antibody detects endogenous levels of Atm around the phosphorylation site of S1981 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized phospho-peptide around the phosphorylation site of human Atm (phospho Ser1981)

  • Uniprot No

    Q13315

  • Alternative names

    ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    ATM serine/threonine kinase(ATM) Homo sapiens The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010],

  • Other

    ATM, Serine-protein kinase ATM

  • Concentration

    1 mg/ml

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