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Bax (phospho Ser184) rabbit pAb

簡要描述：SourceRabbitApplicationsIHC,ELISAReactivityHuman,Mouse,RatDilutionIHC:1:100-1:300

產(chǎn)品型號：
廠商性質(zhì)：生產(chǎn)廠家
更新時間：2025-07-02
訪問量：28

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產(chǎn)品分類

CLASSIFICATION

Primary Antibodies

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詳細(xì)介紹

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-Bax (S184) Polyclonal Antibody detects endogenous levels of Bax protein only when phosphorylated at S184.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Ser184. AA range:143-192
Uniprot No

Q07812
Alternative names

BAX; BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.
Other

BAX, Apoptosis regulator BAX
Mol.Wt (Da)

21184
Concentration

1 mg/ml

Product	Reactivity	Applications	Conjugation	Catalog	Images

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Bax (phospho Ser184) rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Mol.Wt (Da)

Concentration

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