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ASAP2 rabbit pAb

簡要描述：SourceRabbitApplicationsWB

  • 產(chǎn)品型號(hào)：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2025-07-14
  • 訪  問  量：36

詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human,Mouse

  • Dilution

    WB 1:500-2000 ELISA 1:5000-20000

  • Storage

    -20°C/1 year

  • Specificity

    ASAP2 Polyclonal Antibody detects endogenous levels of protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from human protein . at AA range: 640-720

  • Uniprot No

    O43150

  • Form

    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    ArfGAP with SH3 domain, ankyrin repeat and PH domain 2(ASAP2) Homo sapiens This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle

  • Other

    ASAP2 DDEF2 KIAA0400, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (Development and differentiation-enhancing factor 2) (Paxillin-associated protein with ARF GAP activity 3) (PAG3) (Pyk2 C-terminus-associated protein) (PAP)

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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