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ARVC rabbit pAb

簡要描述：SourceRabbitApplicationsWBReactivityHuman

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2025-07-14
  • 訪  問  量：39

詳細介紹

  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human, Mouse

  • Dilution

    WB 1:500-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of ARVC at Human/Mouse

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized peptide derived from human ARVC

  • Uniprot No

    O00192

  • Alternative names

    Armadillo repeat protein deleted in velo-cardio-facial syndrome

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.257% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq, Jun 2010],

  • Other

    ARVCF, ARVC, Armadillo repeat protein deleted in velo-cardio-facial syndrome

  • Concentration

    1 mg/ml

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