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Arrestin-β-1 rabbit pAb2

簡(jiǎn)要描述：SourceRabbitApplicationsWB,IHC,IF,ELISAReactivityHuman,Mouse,RatDilutionWB:1:500-1:2000

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  • 廠(chǎng)商性質(zhì)：生產(chǎn)廠(chǎng)家
  • 更新時(shí)間：2025-07-14
  • 訪(fǎng)  問(wèn)  量：36

詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB,IHC,IF,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Arrestin-β-1 Polyclonal Antibody detects endogenous levels of Arrestin-β-1 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human ARRB1. AA range:369-418

  • Uniprot No

    P49407

  • Alternative names

    ARRB1; ARR1; Beta-arrestin-1; Arrestin beta-1

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    arrestin beta 1(ARRB1) Homo sapiens Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],

  • Other

    ARRB1, Beta-arrestin-1

  • Mol.Wt (Da)

    47066

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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