BRCA1 rabbit pAb

簡要描述：SourceRabbitApplicationsIHC,ELISAReactivityHumanDilutionIHC:1:100-1:300

產(chǎn)品型號：
廠商性質(zhì)：生產(chǎn)廠家
更新時(shí)間：2025-07-15
訪問量：33

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產(chǎn)品分類

CLASSIFICATION

Primary Antibodies

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詳細(xì)介紹

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human
Dilution

IHC: 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

BRCA1 Polyclonal Antibody detects endogenous levels of BRCA1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human BRCA1. AA range:955-1004
Uniprot No

P38398
Alternative names

BRCA1; RNF53; Breast cancer type 1 susceptibility protein; RING finger protein 53
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

BRCA1, DNA repair associated(BRCA1) Homo sapiens This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript varian
Other

BRCA1, Breast cancer type 1 susceptibility protein
Mol.Wt (Da)

207721
Concentration

1 mg/ml

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BRCA1 rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Mol.Wt (Da)

Concentration

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