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Bob 1 rabbit pAb

簡(jiǎn)要描述：SourceRabbitApplicationsIHC

  • 產(chǎn)品型號(hào)：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2025-07-03
  • 訪  問(wèn)  量：22

詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human

  • Dilution

    IHC 1:50-200, ELISA 1:10000-20000

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous Bob 1

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthetic peptide from human protein at AA range: 201-250

  • Uniprot No

    Q16633

  • Alternative names

    POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (BOB-1) (OCA-B) (OCT-binding factor 1)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.,function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the POU2AF1 family.,tissue specificity:B-cell specific.,

  • Other

    POU2AF1 OBF1, POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (BOB-1) (OCA-B) (OCT-binding factor 1)

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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