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Bestrophin-1 rabbit pAb

簡要描述：SourceRabbitApplicationsWB,IHCReactivityHuman,Rat,MouseDilutionWB:1:500-1:2000

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2025-07-03
  • 訪  問  量：22

詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB,IHC

  • Reactivity

    Human,Rat,Mouse

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous Bestrophin-1 protein

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthetic Peptide of Bestrophin-1

  • Uniprot No

    O76090

  • Alternative names

    Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    bestrophin 1(BEST1) Homo sapiens This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008],

  • Other

    BEST1, Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)

  • Concentration

    1 mg/ml

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