BID (phospho Ser78) rabbit pAb

簡要描述：SourceRabbitApplicationsIHC,ELISAReactivityHuman,MouseDilutionWB1:500-2000,IHC:1:100-1:300

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詳細(xì)介紹

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human,Mouse
Dilution

WB 1:500-2000 ,IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-BID (S78) Polyclonal Antibody detects endogenous levels of BID protein only when phosphorylated at S78.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human BID around the phosphorylation site of Ser78. AA range:44-93
Uniprot No

P55957
Alternative names

BID; BH3-interacting domain death agonist; p22 BID; BID
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

BH3 interacting domain death agonist(BID) Homo sapiens This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008],
Other

BID, BH3-interacting domain death agonist
Mol.Wt (Da)

21995
Concentration

1 mg/ml

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