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C/EBP α (phospho Thr226) rabbit pAb

簡要描述:SourceRabbitApplicationsWB,ELISAReactivityHuman,Mouse,Rat,MonkeyDilutionWB:1:500-1:2000

  • 產(chǎn)品型號:
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時間:2025-07-03
  • 訪  問  量:35

詳細介紹

  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human,Mouse,Rat,Monkey

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-C/EBP α (T226) Polyclonal Antibody detects endogenous levels of C/EBP α protein only when phosphorylated at T226.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human C/EBP-alpha around the phosphorylation site of Thr226. AA range:192-241

  • Uniprot No

    P49715

  • Alternative names

    CEBPA; CCAAT/enhancer-binding protein alpha; C/EBP alpha

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    CCAAT/enhancer binding protein alpha(CEBPA) Homo sapiens This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013],

  • Other

    CEBPA, CCAAT/enhancer-binding protein alpha

  • Mol.Wt (Da)

    37575

  • Concentration

    1 mg/ml

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